Mike Boots: After a mostly empirical PhD I was awarded a Royal Society/JSPS post-doctoral fellowship in the Entomology Department of Kyoto University. During this time I developed my interest in theory and was awarded a European Union STA Fellowship to return to Japan to join the mathematical biology group in Kyushu. I then chose to move to Nagasaki as a centre of excellence postdoctoral fellowship in the medical entomology department of the Institute of Tropical Medicine, in order to gain experience of applying models to problems in human disease interactions and to develop my interest in vector ecology. I returned to the UK in 2000, having been awarded a NERC Advanced Fellowship, and subsequently held Readerships at the Universities of Stirling and Sheffield. I was made Professor of Disease Biology in the Department of Animal and Plant Sciences in Sheffield in 2007, moved to Exeter in 2011 and to UC Berkeley in 2015. My brief CV is here.
Postdoctoral Research Associates
Ben Ashby: I joined the Boots lab in July 2014 (Exeter, UK) following my PhD at the University of Oxford (supervised by Sunetra Gupta and Angus Buckling), which was awarded the Thomas Henry Huxley Award and Marsh Prize from the Zoological Society of London for the best zoological doctoral thesis in the UK. My research focuses on the interplay between the ecological and evolutionary dynamics of hosts and their parasites. I use mathematical models (adaptive dynamics, population genetics) and numerical simulations (individual and population level) to understand the evolution of a wide range of host and parasite traits, including resistance, infectivity, virulence, and reproductive strategies. During my post-doc I have reconciled theory on sexual selection and host-parasite coevolution, and I am currently developing new methods at the interface of adaptive dynamics and classic population genetics approaches to understand the importance of ecological feedbacks.
For a full list of publications, see my Google Scholar profile.
Penny Lynch: Having recklessly abandoned undergraduate biology back in 1980, I built a career in finance before finally returning to science via a part-time maths degree and a PhD (co-supervised by Uwe Grimm and Andrew Read) modelling the effects of health interventions on the evolution of life history in disease causing organisms. A large part of my PhD involved modelling the potential disease control benefits and evolutionary consequences of novel interventions targetting malaria vectors. I have maintained my interest in this area, and my current research comprises the development and application of mathematical models which consider vector ecology and life history to explore the potential benefits of new vector control methods. I am also still exploring ways to manage and perhaps even exploit the evolutionary effects of human interventions on vector populations.
Carly Rozins: Before Jointing the Boots lab in September 2016, I was at Queen’s University, in Ontario Canada, completing my PhD in Applied Mathematics. My supervisors at Queen’s were Troy Day and Peter Taylor and my primary research area was mathematical biology. In the past I have primarily developed models for the spread of infectious diseases. After completing my MSc in 2009, I held an internship at Public Health and McGill University, in Montreal Quebec, as a modeller during the swine flu pandemic. Over the past three years, while at Queen’s, I have developed models for the spread and evolution of Marek’s disease, a disease of poultry, within industrial poultry farms. My most recent project on Marek’s disease aims to evaluate the economic impact of controlling virulence evolution within the egg industry. This project is being funded by the Egg Farmers of Canada. Currently Lewis Bartlett and I are developing models to investigate how apiary structure and practices may be driving the evolution of virulence of honey bee pathogens.
Ryosuke Iritani: After graduating from Kyoto University, I entered Kyushu University to work with Yoh Iwasa. While visiting Montpellier (France) and Lausanne (Switzerland), I theoretically studied effects of space on dispersal, cooperation, and parasite-mediated xenophobia, using adaptive dynamics and inclusive fitness theory. Also, I’ve been working on host manipulation of parasites and cancer oncolytic virus dynamics. I finished my PhD in March 2016. In Berkeley, we are going to work on: (1) coevolutionary branching in host-parasite system, (2) host-parasite conflict resolution, and (3) host-parasite spatial structuring.
Visit my website for more details.
Rotem Ben-Shachar: I am a new post-doc in the Boots lab, co-advised by both Mike Boots and Eva Harris. In 2016 I completed my PhD in Computational Biology & Bioinformatics at Duke University, advised by Katia Koelle. I used mathematical and statistical approaches to understand and to characterize the within-host mechanisms driving severe disease caused by dengue virus infection, and assessed how the potential evolution of novel dengue genotypes may impact dengue disease patterns over time. In my post-doc I will be developing dengue population-level models in order to understand the role of asymptomatic infections in transmission dynamics. Furthermore, using data from Nicaraguan cohort studies, I will develop models to understand differences in the spread of dengue, zika and chikungunya in Nicaragua.
Visit my website for more details. for more details.
Senay Yitbarek: I completed my PhD in Biology at the University of Michigan in December of 2016 under the supervision of John Vandermeer. I combined mathematical and empirical approaches to study the population level consequences of spatial networks. My modeling work examined the effects of spatial network structures on multi-species coexistence, ranging from small-world networks to regular random graphs. I complemented this approach with experiments using ant species as a model system in tropical agricultural ecosystems. In 2017, I started as an NSF Postdoctoral Research Fellow in the Boots lab. I am examining the role of spatial network structure on the evolution of multi-pathogen virulence. To this end, I am conducting multi-pathogen experiments in the Plodia system and developing network based disease models.
Lewis Bartlett: I graduated in Zoology from Selwyn College, University of Cambridge in 2013. After working on a collection of projects with UNEP, Microsoft Research, University of York, and University of Exeter’s Environment and Sustainability Institute, I began my NERC-funded PhD with University of Exeter’s Centre for Ecology and Conservation in September 2014. My research background spans a range of evolutionary ecology topics, from quaternary mammal extinctions, to experimental evolution of fungal pathogens. Across these study systems, computational approaches to empirical problems has been a defining common thread. My current work focusses on how spatial structuring of host populations influences pathogen diversity, with specific application to the commercial management of honeybees. Working with University of Georgia and Emory University (GA), we are testing how different beekeeping management regimes affect the evolution of honeybee viruses, especially deformed wing virus, and their parasitic vector the varroa mite. I complement this approach with empirical lab work using our Plodia interpunctella / PiGV system, as well as simulation modelling, based at UC Berkeley.
Laura Ward Alexander: After graduating from University of Georgia with degrees in microbiology and in ecology, my research has focussed on using mathematical models to better understand emerging infectious diseases, both in humans and in wildlife. I worked on projects with the Park Lab at UGA, including the US response to the 2014 West African ebola outbreak. I’ve now moved to UC Berkeley to undertake my PhD, applying epidemiological models to other emerging diseases such as Zika virus.
Elisa Visher: I graduated from Yale University in 2014 with a BS Intensive in Biology and a BA in Anthropology. While at Yale, I focused my studies on evolutionary medicine from both the host and pathogen perspectives. I worked with Paul Turner on projects involving experimental evolution of bacteriophage and Brenda Bradley on a number of projects relating to primate genomics. After finishing my undergrad, I moved to the University of Michigan for 2 years where I worked as a Research Laboratory Technician Associate with Adam Lauring. There, my work focused on characterizing the mutational robustness of influenza A virus. I have now started my PhD at UC Berkeley where I plan to use the Plodia / PiGV empirical system to answer questions about how the structuring of host immune profiles affects viral evolution. I am very interested in using empirical research in model systems to begin to understand how host social structures affect viral evolution.